122 East 38th Street Midtown East Townhouse For Sale

A historic Manhattan townhouse defined by scale, character, and opportunity.

Set in the heart of Murray Hill, this early 20th century townhouse spans approximately 6,500 square feet across six levels, plus cellar and roof. Rich in architectural detail and layered with history, the property presents a rare opportunity to restore, reimagine, or transform a classic New York townhouse into a truly bespoke residence.

Originally purchased in 1906 by Mamie Lincoln Isham, granddaughter of Abraham Lincoln, the home has long been associated with purpose and forward thinking, later serving as the headquarters of an environmental nonprofit and the site of one of Manhattan's first green roofs.

Original elements, including impeccably preserved decorative moldings, fireplaces, and a striking spiral staircase, reflect the home's origins, while ample windows allow natural light to flow throughout. The layout spans multiple levels of living, working, and private space, offering exceptional flexibility for a grand single-family home or live-work configuration.

A private elevator services each level, and the scale and proportions of each floor allow for a wide range of design possibilities. The upper levels open to outdoor space, including a private terrace and rooftop retreat with views of the Chrysler Building and the Empire State Building.

Thoughtful system upgrades, including high-efficiency mechanicals, advanced climate control, and integrated home automation, enhance comfort and energy performance while supporting a more sustainable footprint.

Positioned moments from Park Avenue, Grand Central, and Midtown, the property is ideally situated on a quiet residential street.